CellWell record HH-50244
The progesterone to estradiol ratio predicts fear extinction in mice and humans
Jaime F Nabás; Eric R Velasco; David Fabregat-Safont; Élida Alechaga; Alex Gomez-Gomez; Marta Torrent; Mariana G Fronza; Victoria Mueller; Mohammed R Milad; Rafael Torrubia; Miquel A Fullana; Katharina Schultebraucks; Oscar Pozo; Raul Andero
2026
In plain language
Across mice and humans, a higher ratio of progesterone to estradiol before a fear-extinction task predicted better within-session fear extinction in both species, identifying this hormone ratio as a possible biomarker relevant to fear-related conditions.
- Evidence
- Emerging
- Design
- Animal study
Cite this record: https://thecellwell.org/studies/HH-50244
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