CellWell record HH-495554
Lactobacillus yoelii Lac-2 mediates the mechanism of MAPK signaling pathway involved in the regulation of intestinal barrier and pathogen translocation by Zonulin expression
Zhongyan Liu; Ziqin Zhang; Meixue Ni; Xiaoli Ren; Xiaoqing Guo; Zhenyu Chang; Hailong Dong; Qingxia Wu
Scientific Reports ยท 2026
In plain language
In yak-derived epithelial cells, Lactobacillus yoelii Lac-2 was linked to reduced zonulin expression through MAPK pathway inhibition, while zonulin upregulation impaired tight junctions and increased bacterial translocation.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-495554
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