Studies

CellWell record HH-4954

Effects of melatonin supplementation on blood glycemic indices in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials.

Hadi S; Hadi V; Mohammadzadeh M; Jahangirfard B

Nutrition & metabolism ยท 2026

In plain language

Across 30 randomized trials, melatonin supplementation modestly reduced fasting blood glucose, insulin, and HOMA-IR and improved an insulin sensitivity index, but had no significant effect on HbA1c, with high heterogeneity.

Evidence
Contested
Design
Meta-analysis

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