Studies

CellWell record HH-495025

Ketone Body β-Hydroxybutyrate Enhances Hypothalamic Leptin and Insulin Responsiveness

Kaneko, Kentaro; Takahashi, Nozomi; Ran Xu; Xu, Ran; Kentaro Kaneko; Nozomi Takahashi

Multidisciplinary Digital Publishing Institute · 2026

In plain language

In high-fat diet-fed obese mice, beta-hydroxybutyrate given orally or intracerebroventricularly enhanced anorexigenic responses to leptin and insulin, and chronic central administration suppressed body weight gain.

Evidence
Emerging
Design
Primary research (design unspecified)

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