Studies

CellWell record HH-49396

Beyond inflammation and cholesterol: atherogenic index of plasma mediates the link between hsCRP/HDL-C ratio and depression in US adults NHANES 2015-2020

Jing-Ying Ma; Jue Hu; FaDan Tang; YiLin Meng; Fa Ye; Lin-Lin Hu; Yong-Hua Zhang

2026

In plain language

In 10,357 U.S. adults, the ratio of C-reactive protein to HDL cholesterol showed a nonlinear link to depression risk, partly explained by a blood-lipid marker of atherogenic risk.

Evidence
Emerging
Design
Observational study

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