CellWell record HH-492879
Effect of choline supplementation in presymptomatic APOE ε4 carriers: a pilot study
William J Ray; Yaima L Lightfoot; Ronnie T Trinh; Janelle Fawver-Kahle; Susan Cooper; Li-Huei Tsai; Jonathan Bortz; Isis Trujillo-Gonzalez; Tianheng Zhang; Hulin Wu; Guadalupe J Ortiz Iv; Paul E Schulz
2026
In plain language
In a six-month open-label pilot of 13 asymptomatic APOE ε4 carriers, choline supplementation increased plasma and CSF choline and betaine, with CSF neurofilament light lower at study end.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-492879
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