Studies

CellWell record HH-4805

Neuroprotective effects of icariin in animal models of depression and anxiety: a systematic review of preclinical studies.

He JX; Lin CH; Ling JA; Kuo CL; Lee MS

BMC complementary medicine and therapies ยท 2026

In plain language

A meta-analysis of 23 studies found icariin reduced depression-like behavior in rodent models via neuroprotective, BDNF, and anti-inflammatory pathways, but nearly all animals tested were young adult males.

Evidence
Emerging
Design
Meta-analysis

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