Studies

CellWell record HH-47319

Effects of Supplementation with the Standardized Extract of Saffron (affron®) on the Kynurenine Pathway and Melatonin Synthesis in Rats

Mario De la Fuente Muñoz; Marta Román-Carmena; Sara Amor; Ángel Luís García-Villalón; Alberto E Espinel; Daniel González-Hedström; Miriam Granado García

2023

In plain language

In male rats given a standardized saffron extract for 7 days before sleep, the treatment lowered kynurenine and raised melatonin, testosterone and antioxidant enzyme activity while reducing inflammatory signaling in the pineal gland and liver.

Evidence
Emerging
Design
Animal study

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