CellWell record HH-47164
Inhibition by lithium of glycogen synthase kinase-3 (GSK-3): Possible mechanism of therapeutic action of lithium
D. Hervé
European Psychiatry · 2014
In plain language
This review describes lithium's inhibition of glycogen synthase kinase-3 as a proposed mechanism behind its mood-stabilizing action, based on animal studies, though the exact contribution to clinical effects in humans remains unclear.
- Evidence
- Emerging
- Design
- Narrative review
Cite this record: https://thecellwell.org/studies/HH-47164
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