CellWell record HH-47146
Therapeutic targeting of GSK3β enhances the Nrf2 antioxidant response and confers hepatic cytoprotection in hepatitis C
Yongfang Jiang; Hui Bao; Yan Ge; Wei Tang; Du Cheng; Kaizhong Luo; Guozhong Gong; Rujun Gong
2015
In plain language
In hepatitis C-infected liver cells and patient biopsies, inhibiting GSK3beta with lithium restored the Nrf2 antioxidant response, and patients on long-term lithium carbonate for psychiatric conditions showed less liver injury.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-47146
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