CellWell record HH-47122
Lithium chloride suppresses ferroptosis of induced pluripotent stem cells with ApoE4/E4 from a sporadic Alzheimer's disease patient
Ying Wang; Samuel Anchipolovsky; Piplu Bhuiyan; Luna Sato; Ge Liang; De-Maw Chuang; Huafeng Wei
2026
In plain language
In stem cells from an Alzheimer's patient carrying the ApoE4 gene, lithium chloride improved cell survival and reversed markers of ferroptosis, including iron buildup and lipid damage, while preserving mitochondrial function.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-47122
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