Studies

CellWell record HH-47114

Lithium and its effects: does dose matter?

Mirko Manchia; Pasquale Paribello; Martina Pinna; Luca Steardo; Bernardo Carpiniello; Federica Pinna; Claudia Pisanu; Alessio Squassina; Tomas Hajek

2024

In plain language

This review argues that lithium's mood-stabilizing effect requires blood levels above 0.6 mEq per liter, but lower doses may still lower rates of depressive recurrence in older adults, and microdoses may reduce suicide risk and support cognition.

Evidence
Emerging
Design
Expert review

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