Studies

CellWell record HH-47113

Lithium and neuroprotection: a review of molecular targets and biological effects at subtherapeutic concentrations in preclinical models of Alzheimer's disease

Vanessa de Jesus R De-Paula; Marcia Radanovic; Orestes Vicente Forlenza

2025

In plain language

This review reports that subtherapeutic lithium doses, well below standard psychiatric dosing, reduced amyloid plaques and tau hyperphosphorylation and improved memory in preclinical Alzheimer's models, suggesting a safer path to neuroprotection.

Evidence
Emerging
Design
Expert review

Read it on PubMed

Powered by CellWell

Cite this record: https://thecellwell.org/studies/HH-47113

Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.

This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.