Studies

CellWell record HH-470470

Adaptive laboratory evolution of E. coli to magnesium chloride stress reveals noncanonical routes to broad chaotropic salt resistance

Luke A Fisher; Carleton H Coffin; Trevor Palmiotto; Catherine A Royer; Britney E Schmidt; Jeff S Bowman; Douglas H Bartlett

2026

In plain language

Evolved E. coli isolates grew better in magnesium chloride and other chaotropic salts, but not sodium chloride, and mutations in ptsI and spoT were essential for that tolerance.

Evidence
Emerging
Design
Primary research (design unspecified)

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