Studies

CellWell record HH-465932

The role of the cardiac lymphatic system in heart failure "reverse remodeling": from developmental signals to druggable targets

Tingxuan Huang; Teng Qi; Lingjun Yao; Zhentao Zhu; Chenyu Li; Pengxiang Tang; Zeyu Meng; Zheyu Wen; Tingyu Wang; Sui Liu; Peilin Xie; Zilin Li; Jing Hu

2026

In plain language

This review proposed that impaired cardiac lymphatic vessels in chronic heart failure perpetuate edema, inflammation and fibrosis, and that boosting new lymph vessel growth may support reverse remodeling.

Evidence
Emerging
Design
Expert review

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