Studies

CellWell record HH-460057

Renal Phosphate Reabsorption in Humans Depends on at Least Three Distinct Transporters Unlike in Mice

Ashley L Fernandes; Laurine Lang; Jürgen Klar; Anja Giese; Alexander Ehrmann; Rupert Busch; Hannah Auwerx; Christoph Daniel; Nati Hernando; Isabel Rubio-Aliaga; Carsten A Wagner

2026

In plain language

In human kidney brush-border vesicles, phosphate reabsorption relied on several transporters, with SLC34A1 contributing about 40% in adults versus about 80% in mice, and SLC34A3 about 40% in adults but negligible in mice.

Evidence
Emerging
Design
Primary research (design unspecified)

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