CellWell record HH-458792
The SGK1/ENaC axis in renal injury during salt-sensitive hypertension: from sodium sensing to inflammation
Yan Wang; Meixiang Wu; Jinlan Ma; Ruixin Liu; Delong Duo
2026
In plain language
This perspective proposes that high salt activates SGK1 in immune antigen-presenting cells, raising ENaC sodium entry and inflammation that may sustain kidney injury in salt-sensitive hypertension.
- Evidence
- Emerging
- Design
- Expert review
Cite this record: https://thecellwell.org/studies/HH-458792
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