Studies

CellWell record HH-457689

Stoichiometric calibration of ceruloplasmin activity with copper enables molar quantification and has implications for the estimation of non-ceruloplasmin-bound copper

Alexandra M. Kane; Kurt T.K. Giuliani; Melanie Coogan; Linda Sanders; Richard G. Ruddell; Matthew Burke; Carel J. Pretorius; Jacobus P.J. Ungerer

Clinical Chemistry and Laboratory Medicine (CCLM) ยท 2026

In plain language

Calibrating ceruloplasmin ferroxidase activity against serum copper gave a factor for converting activity to molar concentration, allowing reference intervals and a rough, uncertain estimate of non-ceruloplasmin-bound copper in a large cohort.

Evidence
Emerging
Design
Primary research (design unspecified)

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