Studies

CellWell record HH-454604

LDLR and APOB pathogenic variants predict discordant TSH effect on LDL-C

Jan Kafol; Jaka Šikonja; Matej Mlinarič; Barbara Čugalj Kern; Mihaela Pricop-Jeckstadt; Ana Drole Torkar; Tevž Gorjanc; Andraž Petek; Andreja Lakner; Jernej Kovač; Tadej Battelino; Urh Grošelj

Atherosclerosis · 2026

In plain language

In 738 prepubertal children, TSH was positively associated with LDL cholesterol only in familial hypercholesterolemia caused by LDLR variants, not in APOB variant carriers or children without familial hypercholesterolemia.

Evidence
Emerging
Design
Primary research (design unspecified)

Read it on PubMed

Powered by CellWell

Cite this record: https://thecellwell.org/studies/HH-454604

Produced by the CellWell Research Engine, custom software owned and operated by CellWell. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.

This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.