CellWell record HH-452604
Dysregulation of hepatic deiodinase type I in metabolically associated steatotic liver disease
Nuria López‐Alcántara; Alison-Michelle Naujack; Yingfu Chen; Natalie Taege; Cathleen Geißler; Rebecca Oelkrug; Eva Katrin Wirth; Lutz Schomburg; Anita Boelen; Henriette Kirchner; Jens Mittag
Journal of Molecular Endocrinology · 2025
In plain language
In mice with fatty liver disease, hepatic Dio1 mRNA rose early on a high-calorie diet, but its link to enzyme activity weakened as disease advanced, and raising DIO1 activity did not improve metabolic markers.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-452604
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