Studies

CellWell record HH-447643

Ghrelin Alleviates Aging-Related Cognitive Impairment by Regulating Autophagy-Related Signaling via the SHBG/JNK1/Beclin1 Axis in Microglia

Lixing Zhou; Ying Cheng; Wanyu Zhao; Xuelian Sun; Fengjuan Hu; Meiling Ge; Yan Zhang; Gongchang Zhang; Birong Dong; Xiaolei Liu

2026

In plain language

In aging mice, ghrelin improved cognition and reduced microglial senescence, with effects appearing to run through an SHBG/JNK1/Beclin1 autophagy pathway.

Evidence
Emerging
Design
Primary research (design unspecified)

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