Studies

CellWell record HH-445028

Dietary choline intake and incident dementia in middle-aged and older adults: a prospective cohort study and dose-response meta-analysis

Hui Chen; Tongtong Li; Minyu Wu; Mario H Flores-Torres; Jie Zheng; Zexin Guo; Jie Yu; Benyan Luo; Dan Liu; Yanhui Lu; Changzheng Yuan

2026

In plain language

In 5,301 US middle-aged and older adults, moderate dietary choline intake was associated with lower dementia risk, and a meta-analysis of five cohorts showed risk falling up to about 465 mg per day, then leveling off.

Evidence
Established
Design
Meta-analysis

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