Studies

CellWell record HH-443610

Increased interleukin-6 and hepcidin-25 are associated with restless legs syndrome in rheumatoid arthritis patients

Krasimir Avramov; Snezhana Terziyska; Ivan Yakov; Todor Georgiev; Aneliya Draganova; Kiril Terziyski

Folia Medica ยท 2026

In plain language

Among 32 rheumatoid arthritis patients, those with restless legs syndrome had higher IL-6 and hepcidin-25, lower serum iron and higher disease activity than those without, suggesting inflammation-driven functional iron deficiency.

Evidence
Emerging
Design
Primary research (design unspecified)

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