Studies

CellWell record HH-442164

Effects of high-dose vitamin D supplementation in patients with multiple sclerosis: A systematic review of efficacy and safety

Kholoud Al Ghamdi; Mohammed Alqarni; Ziyad Alamri; Mohand Al Wahhas; Muhammad Alkhaldi; Abdulrahman Alsanni; Ali Fouad Alhawaj

2026

In plain language

In a systematic review of 11 trials, high-dose vitamin D (at least 10,000 IU daily) in multiple sclerosis was safe with monitoring and reduced IL-17-related inflammation, while MRI and clinical effects were inconsistent.

Evidence
Established
Design
Systematic review

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