Studies

CellWell record HH-440232

Network meta-analysis of metformin, probiotics, krill oil, celecoxib, and glucosamine/chondroitin in the treatment of knee osteoarthritis

Keye Chen; Yan Sun; Longkang Cui; Yuchen Zhu; Bingbing Zhang; Haigang Wang

2026

In plain language

In a network meta-analysis of 23 trials in knee osteoarthritis, celecoxib ranked highest for pain reduction, while probiotics and metformin showed potential benefit with low-certainty evidence.

Evidence
Established
Design
Systematic review

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