Studies

CellWell record HH-439942

Soluble IL-2 receptor and memory Treg profiles differentiate early rheumatoid arthritis from undifferentiated arthritis at initial presentation

Xiaoyu Zi; Yifang Shi; Yicong Zhao; Chong Gao; Caihong Wang

2026

In plain language

Treatment-naive early RA was distinguished from undifferentiated arthritis by higher soluble IL-2 receptor and IL-6 levels and memory regulatory T-cell expansion, with an eight-feature immune signature reaching an optimism-corrected AUC of 0.959.

Evidence
Emerging
Design
Primary research (design unspecified)

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