CellWell record HH-439720
FGL1-hepcidin axis in iron homeostasis and disease
Saboor M; Rahim RA; Dad SN; Mansoor HM; Nasser MM; Yusuf AM
Clinica chimica acta; international journal of clinical chemistry ยท 2026
In plain language
This review describes FGL1 as a liver-derived protein that suppresses hepcidin by binding BMP ligands and also acts on the immune checkpoint LAG-3, linking iron metabolism to immune regulation in several diseases.
- Evidence
- Emerging
- Design
- Expert review
Cite this record: https://thecellwell.org/studies/HH-439720
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