CellWell record HH-436587
Iron Overload and Male Hypogonadism: A Systematic Review of the Hypothalamic-Pituitary-Gonadal Axis and Evidence Suggesting Ferritin-Related Burden Thresholds
Julian Borges; Rudolph Eberwein
2026
In plain language
This systematic review of 13 human studies linked iron overload to hypogonadotropic hypogonadism in hemochromatosis and thalassemia, proposing ferritin thresholds as hypothesis-generating only, given very low to low certainty of evidence.
- Evidence
- Emerging
- Design
- Preprint
Cite this record: https://thecellwell.org/studies/HH-436587
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