Studies

CellWell record HH-435401

Synthesis of axially chiral benzochalcogenophene derivatives and their anti-proliferative activities in cancer cells

Nakaie K; Inoue T; Mikyu R; Otsuki N; Ashihara E; Furuta T

Bioorganic & medicinal chemistry ยท 2026

In plain language

The axially chiral benzothiophene (S)-2 inhibited proliferation of pancreatic and leukemia cancer cell lines more strongly than its selenium analog, and caused DNA damage and caspase-dependent apoptosis.

Evidence
Emerging
Design
Primary research (design unspecified)

Read it on PubMed

Powered by CellWell

Cite this record: https://thecellwell.org/studies/HH-435401

Produced by the CellWell Research Engine, custom software owned and operated by CellWell. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.

This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.