Studies

CellWell record HH-431514

Intestinal permeability and the zonulin pathway: tight junctions, mucosal immunity, dietary modulators and clinical relevance

David Granizo Bermejo; Guillermo García-Pérez-de-Sevilla; Antonio Molina-López

Frontiers in Nutrition · 2026

In plain language

This narrative review links dietary factors such as excess sugar, fat, salt and alcohol to impaired intestinal barrier integrity, and notes that zonulin is the only known endogenous protein that reversibly regulates tight junction permeability.

Evidence
Emerging
Design
Primary research (design unspecified)

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