Studies

CellWell record HH-4299

Effect of high-dose intravenous ascorbic acid on microcirculation and endothelial glycocalyx during sepsis and septic shock: a double-blind, randomized, placebo-controlled study.

Belousoviene E; Pranskuniene Z; Vaitkaitiene E; Pilvinis V; Pranskunas A

BMC anesthesiology · 2023

In plain language

A randomized controlled trial on Vitamin C found that as an indicator of glycocalyx thickness, the perfused boundary region was lower in capillaries of the 5-9 μm diameter in the AA group than placebo after the first dose of AA.

Evidence
Emerging
Design
Randomized controlled trial
Studied in
Human

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