CellWell record HH-41412
ACMG Practice Guideline: lack of evidence for MTHFR polymorphism testing
Hickey SE; Curry CJ; Toriello HV
Genetics in medicine : official journal of the American College of Medical Genetics ยท 2013
In plain language
This practice guideline concluded that meta-analyses disproved links between elevated homocysteine and coronary heart disease risk and between MTHFR polymorphism status and venous thromboembolism risk, finding the test has minimal clinical utility for routine thrombophilia evaluation.
- Evidence
- Emerging
- Design
- Meta-analysis
Cite this record: https://thecellwell.org/studies/HH-41412
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