Studies

CellWell record HH-41405

Targeting hepcidin to restore oral iron efficacy after vertical sleeve gastrectomy

Xiaozhuo Tan; Chong Cao; Xianjue Huang; Rong Hua; Randy J Seeley; Qiyuan Yao; Bo Xu; Yikai Shao

2026

In plain language

In mice and patients after vertical sleeve gastrectomy, oral iron supplementation failed to correct deficiency because it triggered a rise in the hormone hepcidin that trapped iron inside cells, and curcumin restored iron release in mice by suppressing hepcidin.

Evidence
Emerging
Design
Animal study

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