CellWell record HH-41301
Impact of the common MTHFR 677C→T polymorphism on blood pressure in adulthood and role of riboflavin in modifying the genetic risk of hypertension: evidence from the JINGO project
Ward M; Hughes CF; Strain JJ; Reilly R; Cunningham C; Molloy AM; Horigan G; Casey M; McCarroll K; O'Kane M; Gibney MJ; Flynn A; Walton J; McNulty BA; McCann A; Kirwan L; Scott JM; McNulty H
BMC medicine · 2020
In plain language
In 6,076 Irish and Northern Irish adults, the MTHFR 677TT gene variant was linked to a 42% higher hypertension risk, rising to a 3-fold higher risk when combined with low riboflavin status.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-41301
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