CellWell record HH-409135
Dissecting the causal pathway linking HbA1c to oral cavity cancer via immune cell modulation: a bidirectional mendelian randomization analysis
Jieqi Wang; Zhe Zhang; Yujia Wang; Bowen Li; Meihua Zheng; Jinsong Li
2026
In plain language
Genetically higher HbA1c was causally associated with slightly lower oral cavity cancer risk, while in lab tests advanced glycation products impaired CD8+ T cell function against oral cancer cells.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-409135
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