Studies

CellWell record HH-407815

TANGENT study design: a phase III, randomized study of emactuzumab for the treatment of tenosynovial giant cell tumors

Hans Gelderblom; Emanuela Palmerini; Michiel van de Sande; Javier Martin-Broto; Gabriel Tinoco; Elyse Seltzer; Madhu Davies; Ruth Coll; Sander Veltkamp; Jean-Yves Blay

2026

In plain language

This protocol describes a randomized, double-blind phase III trial comparing a short intravenous CSF-1R antibody with placebo in adults and adolescents with tenosynovial giant cell tumors not amenable to surgery.

Evidence
Established
Design
Randomized controlled trial

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