Studies

CellWell record HH-40255

Genetic Polymorphisms Associated with Lithium Response in Bipolar Disorder: An Integrative Review and In Silico Protein-Protein Interaction Analysis

Ovinuchi Ejiohuo; Aleksandra Szczepankiewicz

2026

In plain language

Structural modeling of BDNF and NR3C1 gene variants linked to lithium response in bipolar disorder found that these variants stabilized their proteins' interactions with binding partners while preserving overall protein shape, though this remains a computational, not clinical, finding.

Evidence
Emerging
Design
Narrative review

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