CellWell record HH-38852
Vitamin C alleviates PM2.5-induced thyroid injury and ferroptosis by regulating the IL-17A/IL-17RA/ACT1 signaling pathway
Dong X; Han X; Gao J; Li C; Luo Z; Zhu Z; Su Y; Yao S; Zhang F; Xu J; Zhang L; Li H; Zhang C; Wu W
Ecotoxicology and environmental safety ยท 2025
In plain language
In female rats and rat thyroid cells, fine particulate air pollution triggered inflammation and iron-dependent cell death in thyroid tissue, and vitamin C treatment reduced this damage by dampening an inflammatory signaling pathway.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-38852
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