CellWell record HH-387960
Homocysteine Drives Hippocampal Blood-Brain Barrier Disruption and Cognitive Decline Under Chronic Stress via DNA Hypomethylation of Cav1.2
Mao-Yang Zhou; Jin-Shan Li; Zhao-Xin Sun; Jie Yin; Yun Zhao; Fang Xie; Xue Wang; Sheng-Hui Zhang; Zhao-Wei Sun; Ling-Jia Qian
2026
In plain language
Elevated hippocampal homocysteine under chronic stress disrupted the blood-brain barrier and impaired cognition; B vitamin supplementation reversed these effects in rats.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-387960
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