Studies

CellWell record HH-387387

Freeze-Dried Poecilobdella manillensis Powder Regulates Cholesterol Homeostasis to Alleviate Hyperlipidemia

Dezhi Yang; Qingmei Hu; Feng Shi; Xueling Chen; Yiquan Lin; Cuihua Fu; Fang Zhao; Xiaoju Zou; Xiaoxu Bi; Zichao Liu

2026

In plain language

In high-fat-diet-fed ApoE-deficient mice, freeze-dried leech powder lowered triglycerides, total and LDL cholesterol, raised HDL cholesterol, and shifted liver cholesterol synthesis and excretion genes, while reducing foam cell formation in macrophages.

Evidence
Emerging
Design
Primary research (design unspecified)

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