CellWell record HH-3790
Different pharmacokinetics of lithium orotate inform why it is more potent effective and less toxic than lithium carbonate in a mouse model of mania
Pacholko AG and Bekar LK
Journal of Psychiatric Research ยท 2023
In plain language
Lithium orotate more strongly blocked amphetamine hyperlocomotion at lower salt dose and did not reproduce selected creatinine TSH or thirst changes -- Mouse mania proxy and short toxicology cannot establish human mood efficacy or comparative safety
- Evidence
- Emerging
- Design
- Animal study
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-3790
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