CellWell record HH-374168
B111-02 Low-Fiber Diet Promotes Lung Tumorigenesis via Gut Microbiota-Dependent Expansion of Myeloid-Derived Suppressor Cells and Metabolite Dysregulation
C. Mccormick; Y. Li; E. Sanchez; J. Tsay; D. Sterman; L. Segal; Q. Li
American Journal of Respiratory and Critical Care Medicine ยท 2026
In plain language
In a mouse lung adenocarcinoma model, a low-fiber diet increased tumor burden and reduced survival through gut microbiota-dependent expansion of myeloid-derived suppressor cells and inflammatory signaling.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
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