CellWell record HH-374004
Gut complement C1q and C3 interact with Clostridioides difficile spores via CdeM and contribute to pathogenesis.
Marjorie Pizarro-guajardo; Christian Brito-Silva; Pablo Castro-Córdova; Nicolás Montes-Bravo; E. Callegari; Fernando Gil; D. Paredes-Sabja
bioRxiv · 2026
In plain language
Gut complement proteins C1q and C3 directly bound Clostridioides difficile spores, enhancing epithelial entry and contributing to disease recurrence.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-374004
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