Studies

CellWell record HH-356847

Leonurine ameliorates experimental type 2 diabetes through gut microbiota remodeling, enhanced butyrate production, and MPC2 activation to restore GLP-1 secretion

Yaoyuan Zhang; Wanyi Chen; Xinyuan Yu; Jianhua Feng; Abdul Sammad; Zhenbo Wang; Kai Yin

2026

In plain language

In diabetic mice, leonurine improved glucose tolerance and raised GLP-1, an effect linked to increased gut butyrate-producing bacteria and butyrate activation of MPC2 in intestinal L cells.

Evidence
Emerging
Design
Primary research (design unspecified)

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