CellWell record HH-352694
Vancomycin relieves tacrolimus-induced hyperglycemia by eliminating gut bacterial beta-glucuronidase enzyme activity
Peixia Li; Rui Zhang; Jinping Zhou; Pengpeng Guo; Yani Liu; Shao-Jun Shi
Gut microbes ยท 2024
In plain language
In mice with tacrolimus-induced hyperglycemia, vancomycin reduced gut bacterial beta-glucuronidase activity and bile acid levels, which raised GLP-1 secretion and prevented glucose disorder and insulin resistance.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-352694
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