CellWell record HH-3467
Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1
Illing AC, Shawki A, Cunningham CL, Mackenzie B
Journal of Biological Chemistry ยท 2012
In plain language
The intestinal iron transporter DMT1 also carries cadmium, manganese, and cobalt with equal or higher affinity than iron, explaining how low iron status can raise cadmium absorption through shared-transporter competition.
- Evidence
- Established
- Design
- Cell-culture study
- Studied in
- Cell / in vitro
Cite this record: https://thecellwell.org/studies/HH-3467
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