Studies

CellWell record HH-338652

Developmental pharmacokinetics of indomethacin in preterm neonates: Severely decreased drug clearance in the first week of life

Wojciech Krzyzanski; Bradley Stockard; Andrea Gaedigk; Allison Scott; Whitney Nolte; Kim Gibson; J Steven Leeder; Tamorah Lewis

2023

In plain language

Indomethacin clearance is severely reduced in preterm neonates during the first week of life, necessitating model-informed precision dosing rather than standard regimens.

Evidence
Emerging
Design
Primary research (design unspecified)

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