Studies

CellWell record HH-338164

Pharmacokinetics and Bioavailability of Anti-follicular stimulating hormone receptor single chain variable fragment (Anti-FSHr scFV) in Rats: A Comparative Study of Oral and Intravenous Administration

Nontakorn Kwanmuang; Pimnara Maneenak; Manasanan Vacharasiritham; Rungsima Wachirapornpruet; Surumpa Dannoravasonti

2026

In plain language

In rats, an anti-FSH receptor antibody fragment in alginate microspheres reached 26.45% oral bioavailability compared with intravenous dosing, with lower peak levels, supporting further development of an oral contraceptive for macaques.

Evidence
Emerging
Design
Primary research (design unspecified)

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