Studies

CellWell record HH-338111

Absolute Bioavailability and Absorption, Distribution, Metabolism, and Excretion of [14C]Xevinapant, a Potent, Oral, Small-Molecule IAP Inhibitor

Annick Menetrey; Valérie Nicolas-Metral; Marie-Claude Roubaudi-Fraschini; Tri Tat; Yuan Zhao; Yulia Vugmeyster; Karthik Venkatakrishnan; Felix Rohdich; Holger Scheible

2026

In plain language

Xevinapant demonstrated 57.8% oral bioavailability with rapid absorption and predominantly fecal excretion of metabolites in healthy adults.

Evidence
Established
Design
Clinical trial

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