CellWell record HH-338080
First-pass effect of coumarin in man
Ritschel WA; Brady ME; Tan HS
International journal of clinical pharmacology and biopharmacy ยท 1979
In plain language
In a crossover study in humans, coumarin was fully absorbed orally, yet only about 2-6% reached the circulation unchanged, indicating an extensive first-pass effect.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-338080
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